What is Glutathione?

Glutathione – Antioxidant, Detoxifier, Cell Protector

Immunocal® is a patented, proven, SAFE and effective source of the RATE LIMITING precursor for NATURAL intracellular glutathione (GSH) production.


What is glutathione, also known as GSH?

Glutathione is a naturally occurring antioxidant and detoxifier which is so important that without it – you die! Take the time to read the following information, find out how increasing levels of glutathione in your body will help prevent illness and disease – including cancer, the dreaded killer of the 21st century. That’s right, CANCER! Immunocal® has anti-cancer patents and tons of documentation. Please investigate, everything about Immunocal® is supported by validated scientific research.

The Immunocal® and Immunotec® Research story begins in 1978 at McGill University, Montreal Canada. Dr. Gustavo Bounous and his colleagues were studying a natural food source for the immune systems of all mammals. This food source provided every cell of the body with building blocks necessary to produce glutathione, a molecule so important that life cannot exist without it. Every single cell in your body relies on the production and existence of glutathione. Without it – you die! Glutathione is a “tripeptide” ( made of three proteins ). Immunocal® is proven and patented to raise glutathione.

Immunocal®: A natural source of the glutathione precursor cysteine, for the maintenance of a strong immune system. (Approved Claim with Health Canada)


components to make glutathione

Glutathione is made naturally within every cell of your body. It consists of 3 amino acids; GLUTAMATE, GLYCINE AND CYSTEINE. Glutamate and Glycine are plentiful in our food chain, however Cysteine is not, therefore it is the “rate limiting factor” for Glutathione production in the cell.

Immunocal® is a natural source of Cysteine. Cysteine is two cystine (note spelling) molecules linked by a natural and delicate bond, which is what makes Immunocal® so unique and powerful. Cystine (note spelling) supplements, including N-Acetylcysteine are not ideal for raising Glutathione and research shows potential complications or toxic side effects.

Glutathione supplements are ineffective because the molecule is too big to cross the cell membrane and simply gets digested.

Glutathione (GSH) is the body’s own health ‘AID to Energy’ – Antioxidant, Immune Booster, Detoxifier and Energy enhancer. This small protein, produced naturally in the body, supports these four crucial functions. In fact, your life depends upon glutathione. Without it, your cells would disintegrate from unrestrained oxidation, your body would have little resistance to bacteria, viruses and cancer, and your liver would cease functioning from the accumulation of toxins.

Over time, as we age, our glutathione levels naturally decrease. Even in our younger years, glutathione levels can be challenged at times, depending on many factors, such as: exposure to toxins and other environmental factors, lack of sleep, poor appetite, exposure to viruses and bacterias. All these things require extra use of glutathione in order for the body to try to maintain healthy cells. So, even as children, teens, young adults, adults, middle aged, seniors and the very old, supplementing with Immunocal® to optimize natural production of glutathione is a very wise choice. As we age, this choice becomes a critical factor to our longevity.



The Roles of Glutathione

Medical science has described literally dozens of roles that glutathione plays in your body.
However, the four most important roles of glutathione can be summarized by the acronym:

A I D = E2
These letters stand for:

  • Antioxidant
  • Immune support
  • Detoxifier
  • Energy

Let’s look at these four critical processes driven by glutathione:


Dr. Jimmy Gutman, explains glutathione

Immunocal contains the precursors for natural glutathione production in your cells.



A – Glutathione – “Your Master Antioxidant

Over the past thirty years, advances in the study of antioxidants have grown to the point that a whole new branch of medicine has developed called “Free Radical Biology” which focuses on oxidant/antioxidant balance. These scientists have elaborated upon several hundred different disease processes where antioxidants play a vital role. The shelves of natural food stores and pharmacies are resplendent with a large array of different antioxidants offered. However, although these antioxidants including vitamin C and vitamin E are usually “natural”, they are not natural to your body. If you do not ingest these vitamins, they will not be found in your cells naturally. Given the importance of antioxidation in hundreds of different disease processes, one poses the question – “What antioxidant does the body manufacture to ward off these processes?” Glutathione is the most abundantly produced antioxidant in the body. In fact, the presence of this tiny molecule is crucial for the functioning of all of the other antioxidants we know of, which is why Glutathione has been given the title;  “Master Antioxidant”.

I – Glutathione – “Food for the Immune System”

Your immune system is constantly on the prowl for pathogens and foreign antigens — agents of cellular damage, toxicity and disease. These antigens include viruses, bacteria, parasites, fungi and even pre-cancerous cells. To neutralize these pathogens the body needs an abundant supply of glutathione. If it doesn’t have enough, some of the invaders will get through, infecting the body and/or contributing to aging, long-term accumulative damage — even eventual cancer. We can’t avoid illness and aging altogether — although a few scientists are pursuing this age-old dream — but by keeping our intracellular glutathione levels up we also keep our immune system on full alert and fully armed. Dr. Gustavo Bounous, discoverer of Immunocal®, has focused on glutathione as support for the immune system. “ The limiting factor for the proper activity and multiplication of our lymphocytes (white blood cells) is the availability of glutathione”. Dr. Bounous’ research at McGill University has spawned countless additional research papers worldwide, examining this phenomenon. Over 100,000 articles about glutathione can be found on PubMed.(Opens New Window)

D – Glutathione – “Detoxification System”

Hundreds of toxins are eliminated by the GSH enzyme system, including drug breakdown products, pollutants, carcinogens and radiation damage. It’s no surprise that GSH concentrations are highest in the liver, the body’s major detoxifying organ. We inhale and ingest natural and synthetic toxins every day of our lives and can’t possibly avoid them, especially in our technological times, our congested and polluted cities and with our bio-engineered food supplies. Experimental studies have shown that low glutathione levels lead to poor liver and kidney function, and result in unnecessarily large quantities of toxins circulating through the body. There, they continuously damage individual cells and organs. The list of toxins eliminated include cigarette smoke, automobile exhaust and heavy metals. Physicians regularly use drugs to elevate glutathione levels in critical illnesses like acetaminophen overdose and severe liver failure.

E2 – Glutathione – “Energize Yourself”

Our cells are like little machines, running 24 hours a day. Where does the energy to fuel this constant activity come from? The answer is quite complicated but science has identified tiny structures within our cells called “mitochondria” which serve as tiny batteries inside the cell. Like any source of fuel, continually burning, waste products are a result. The mitochondria literally burn up oxygen and as a result are prone to overload and damage and are limited in their ability to continue working unless these breakdown products like oxyradicals are removed. The major substance produced by the cell to keep these mitochondria “cool” and efficient, is glutathione. This translates into more energy and more strength. Raising glutathione has become a focus for many studies from sports medicine to anti-aging for this reason.



What Causes Us to LOSE Glutathione (GSH)?

Every day our bodies are exposed to factors that drain our levels of glutathione: stress, pollution, radiation, infection, drugs, poor diet, aging, injury and fatigue. These all contribute to glutathione depletion which, in turn, leads to cellular aging, disease and death. “Concern about maintaining one’s glutathione levels will eventually be on par with other health maintenance issues.” says Dr. Bounous, discoverer of Immunocal®.

Immunocal® Can Fix the Problem

Immunocal® is proven and patented to raise glutathione. It is a natural source of the glutathione precursor cysteine, for the maintenance of a strong immune system. (Approved Claim with Health Canada opens in new window)


There are other synthetic ways in which glutathione levels may be raised, but the high level of side effects and short duration of action limits their usefulness. In contrast, Immunocal® is extremely effective and has negligible side effects when used as directed. It is a protein isolate from milk, but has an insignificant amount of lactose (<1%); therefore, it is easily tolerated by lactose intolerant individuals.


Don’t you think its time to start optimizing your glutathione levels?

Look around you, is there anyone in your life who is sick? Your answer is probably yes, most people today are not lucky enough to have avoided being touched by death or disease at some point. Immunocal® is the answer… The question is, who is next on the list to become sick? Had they optimized their glutathione levels, their immune system would have a better ability to fight off the illness.


Why should you worry about this now?

Viruses, bacterial infections, cancers, environmental diseases, auto-immune disorders, etc. are all on the rise. Are you going to wait until you or someone you love acquires one or more of these diseases or do you want to do what you can now to prevent them? All of these threats to our immune systems (our very existence) are running rampant all over the globe.


How do you know if you need more of this precious molecule?

Many years ago, before the industrial revolution, our food chain supplied plenty of the raw materials needed to produce this molecule. Presently, our environment has become very toxic. This is the root of our problem, we cannot avoid pollution, toxins and radiation. Most of the air and water on this planet has become mildly poisonous. Your body has its own defence mechanism to combat and eliminate these invaders, called glutathione. The problem is, the present food supply doesn’t take into consideration the increased demand these environmental stresses have caused, therefore many of us today are faced with critically low glutathione levels and we are not even aware of its presence in our bodies.


The following is an excerpt from the book;


by James F. Balch, M.D. 

Pg. 97 - Over the years, the accumulation of toxins in the air and water pollutants, processed foods, and chemical exposure takes its toll on the amount of available glutathione in our bodies – a cancer waiting to happen?


Immunocal® is the result of over 33 years of bona fide scientific research.

It is a milk serum, whey protein isolate which is 90% protein, and extremely high in bio-activity. Immunocal® is the standard to which all other whey proteins on the market are measured today, yet none can compare because of the medical science, patents, references available and proprietary specifications that all make Immunocal® totally unique and extremely powerful.



Sound too good to be true?

Keep reading, we will show you all the proof…


The Science of Glutathione

By Patricia A.L. Kongshavn, Ph.D

Glutathione is a small molecule found in almost every cell. It cannot enter most cells directly and therefore must be made inside the cell, from its three constituent amino acids: glycine, glutamate and cysteine. The rate at which glutathione can be made depends on the availability of cysteine, which is relatively scarce in foodstuffs. Furthermore, the cysteine molecule has a sulfur-containing portion which gives the whole glutathione molecule its ‘biochemical activity’, i.e. its ability to carry out the following vitally important functions:

Firstly, glutathione is the major antioxidant produced by the cell, protecting it from ‘free radicals’ (‘oxygen radicals’, ‘oxyradicals’). These highly reactive substances, if left unchecked, will damage or destroy key cell components (e.g. membranes, DNA) in microseconds. Oxyradicals are generated in the many thousand mitochondria located inside each cell, where nutrients like glucose are burnt using oxygen to make energy. (Mitochondria can be thought of as the batteries that provide the power for the cells to operate). Oxyradicals also come from pollutants, from UV radiation and other sources. In addition, glutathione recycles other well-known antioxidants such as vitamin C and vitamin E, keeping them in their active state.

Secondly, glutathione is a very important detoxifying agent, enabling the body to get rid of undesirable toxins and pollutants. It forms a soluble compound with the toxin that can then be excreted through the urine or the gut. The liver and kidneys contain high levels of glutathione as they have the greatest exposure to toxins. The lungs are also rich in glutathione partly for the same reason. Many cancer-producing chemicals, heavy metals, drug metabolites etc. are disposed of in this way.

Thirdly, glutathione plays a crucial role in maintaining a normal balance between oxidation and anti-oxidation. This, in turn, regulates many of the cell’s vital functions, such as the synthesis and repair of DNA, the synthesis of proteins and the activation and regulation of enzymes.

Fourthly, glutathione is required in many of the intricate steps needed to carry out an immune response. For example, it is needed for the lymphocytes to multiply in order to develop a strong immune response, and for ‘killer’ lymphocytes to be able to kill undesirable cells such as cancer cells or virally infected cells.

The importance of glutathione cannot be overstated. It has multiple roles as indicated and, indeed, as one examines each system or organ more closely, the necessity for glutathione becomes increasingly evident. Glutathione values decline with age and higher values in older people are seen to correlate with better health, underscoring the importance of this remarkable substance for maintaining a healthy, well-functioning body.



Glutathione – The Undiscovered “Natural Drug”

By Patricia A.L. Kongshavn, Ph.D
Former Professor: Department of Medicine, McGill University, Montreal, Canada

A recent press release by CBS highlighted the need for a “universal or all-purpose drug” able to combat any germ or toxic chemical released by hostile forces. In general, the idea would be to bolster the defenses we already possess, in particular the immune system, to fight against infections and cancer.

CBS made brief mention of two substances, cysteine and glutathione, that deserve much greater attention. Glutathione is a key substance found in every cell in our body, and may be thought of as a “naturally occurring universal drug” – and one without adverse side effects! It is the cell’s most important antioxidant, neutralizing “free radicals” that would otherwise damage or destroy the cells. The body produces free radicals during metabolism. Under any form of stress, such as chemical toxicity or bacterial infections, the body generates many more free radicals. If glutathione is in short supply, these free radicals can overwhelm the cell. Exposure to radiation from sunlight or other sources also results in increasing highly reactive free radicals that likewise our bodies need to neutralize. Glutathione is also the main detoxifying agent in the body. It converts damaging chemical substances (toxins) into harmless products that the body eliminates. Such chemicals include cancer-producing substances, heavy metals, herbicides, pesticides, smoke and other pollutants. Thus, glutathione provides important protection against many environmental hazards.

The liver is particularly rich in glutathione for this purpose. The immune system is our main defense against infection. Once again, glutathione plays a vital role, enabling the immune system to function optimally, which it cannot do when glutathione is deficient. For example, the cells of the immune system (lymphocytes) cannot multiply as much, cannot produce as many antibodies, and cannot kill unwanted cells like cancer cells or those infected with a virus.

Glutathione deficiency also adversely affects other systems and organs such as the lungs, the nervous system, and the intestinal tract. It is on record that there are many medical disorders associated with glutathione deficiency. These include AIDS and cancer wasting, some intestinal disorders, lung diseases, over-trained athletes syndrome and trauma. Furthermore, as we age, glutathione levels decrease which no doubt explains, in part, an older person’s lowered resistance to disease.

Glutathione is a very small protein made inside the cells from three amino acids obtained ultimately from our food or supplementation. One of these amino acids, cysteine, gives the glutathione its antioxidant and detoxifying properties. This amino acid is relatively rare in foodstuffs and this can lead to glutathione deficiency, even in healthy people. For example, one study demonstrated that, by feeding a cysteine enriched food product, namely Immunocal®, glutathione values increased by 35.5% in the lymphocytes of normal young adults. (see reference below)

It is well documented that glutathione sold as a dietary supplement is mostly destroyed during digestion and therefore is of little use. Cysteine itself is toxic and suffers the same fate unless chemically modified. Practitioners use N-acetyl cysteine as a supplement, but it has certain unpleasant side effects, even in moderate doses. Thus, the best source for cysteine supplementation is from cysteine-rich foodstuffs. It is normally present in food as the stable form, cystine (2 molecules of cysteine linked together). Our bodies digest, absorb, and carry cystine to the cells where they convert it into cysteine. Since heat or mechanical stress etc., easily split cystine into cysteine (where digestion destroys it), raw unprocessed foods or special food supplements high in bioactive cysteine (cystine) provide the best source of this vital amino acid.

Sixty years ago, Florey and Fleming revolutionized the medical treatment of infection with the discovery of antibiotics that act against a broad range of bacteria. Glutathione, a “natural drug”, perhaps in the same way could provide a significant contribution towards defending ourselves against the growing number of diverse biological and chemical hazards facing our society today.

Lands L.C., Grey V.L., Smountas A.A.
Effect of supplementation with a cysteine donor on muscular performance. J Appl Physiol 8713815, 199



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